Itgb2 CLIA Kit for Mouse(Mus musculus) | EIAab.comItgb2 CLIA Kit for Mouse(Mus musculus)

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Itgb2 (Gene name),

Integrin beta-2 (Protein name ), ITB2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Itgb2;

Protein name:

Integrin beta-2;

Alternative:

Complement receptor C3 subunit beta;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;

CD:

CD18;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9 (By similarity). Interacts with FGR.

Function:

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

771

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

771:

NDNPLFKSAT | TTVMNPKFAE | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07974

SMR:

P11835

String:

P11835

Pfam:

PF08725

UniGene:

Mm.1137

KEGG:

mmu:16414

Uniprot:

P11835

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ELISA Kit for Mouse Integrin beta-2

Cat.:

E0236h

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96T

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ELISA Kit for Mouse Integrin beta-2

Cat.:

E0236p

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96T

ELISA Kit for Mouse Integrin beta-2

Cat.:

E0236b

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96T

ELISA Kit for Mouse Integrin beta-2

Cat.:

E0236m

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96T

CLIA Kit for Mouse Integrin beta-2

Cat.:

U0236b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Integrin beta-2

Cat.:

U0236m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Integrin beta-2

Cat.:

U0236p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Integrin beta-2

Cat.:

U0236h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Integrin beta-2

Cat.:

P0236Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Integrin beta-2

Cat.:

P0236Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Integrin beta-2

Monoclonal Antibody for Mouse Integrin beta-2

Protein for Mouse Integrin beta-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Nucleotide sequence of the cDNA from the mouse leukocyte adhesion protein CD18."
Wilson R.W. , O'Brien W.E. , Beaudet A.L.
Nucleic Acids Res.17:5397-5397(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6 X CBA.
tissue: Thymus.
2.

"Mouse macrophage beta subunit (CD11b) cDNA for the CR3 complement receptor/Mac-1 antigen."
Zeger D.L. , Osman N. , Hennings M. , McKenzie I.F. , Sears D.W. , Hogarth P.M.
Immunogenetics31:191-197(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Mouse macrophage beta subunit (CD11b) cDNA for the CR3 complement receptor/Mac-1 antigen."
Kofler R.
Immunogenetics33:77-77(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO N-TERMINUS
4.

"Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins."
Xu J. , Gao X.-P. , Ramchandran R. , Zhao Y.-Y. , Vogel S.M. , Malik A.B.
Nat. Immunol.9:880-886(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION DURING LUNG INJURY
5.

"c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration."
Baruzzi A. , Iacobucci I. , Soverini S. , Lowell C.A. , Martinelli G. , Berton G.
FEBS Lett.584:15-21(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FGR

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